2011年11月18日星期五

植物碱基替换速率变异的模式和原因

The Patterns and Causes of Variation in Plant Nucleotide Substitution Rates

http://www.annualreviews.org/doi/abs/10.1146/annurev-ecolsys-102710-145119

种间杂种不亲和的遗传学

The Genetics of Hybrid Incompatibilities

http://www.annualreviews.org/doi/abs/10.1146/annurev-genet-110410-132514

这篇综述给出了种间杂种不亲和的研究方法、可能机制。

2011年11月16日星期三

good intro for beamer

http://programming-r-pro-bro.blogspot.com/search/label/beamer

Slopegraphs - a useful tools

1. for introduction of slopegraphs
http://charliepark.org/slopegraphs/
2. for generating slopegraphs with R
http://www.jameskeirstead.ca/r/slopegraphs-in-r/

2011年11月8日星期二

outcrossing and selfing in plants - evolutionary and genomic consequence

  1. Boris Igic, Russell Lande, Joshua R. Kohn
    DOI: 10.1086/523362
    Stable URL: http://www.jstor.org/stable/10.1086/523362
  2. No Access
    Genomic Consequences of Outcrossing and Selfing in Plants(pp. 105-118)  
    Stephen I. Wright, Rob W. Ness, John Paul Foxe, Spencer C. H. Barrett
    DOI: 10.1086/523366
    Stable URL: http://www.jstor.org/stable/10.1086/523366

2011年11月6日星期日

funnel plot

A funnel plot is a scatterplot of treatment effect against a measure of study size. It is used primarily as a visual aid to detecting bias or systematic heterogeneity. A symmetric inverted funnel shape arises from a ‘well-behaved’ data set, in which publication bias is unlikely. An asymmetric funnel indicates a relationship between treatment effect and study size.

A funnel plot is a useful graph designed to check the existence of publication bias in systematic reviews and meta-analyses. It assumes that the largest studies will be near the average, and small studies will be spread on both sides of the average. Variation from this assumption can indicate publication bias.

http://en.wikipedia.org/wiki/Funnel_plot

http://ouseful.files.wordpress.com/2011/10/cancerdatafunnelplot.png?w=600&h=419

2011年11月3日星期四

constrained elements in the human genome as revealed by mammalian alignments of 29 genomes

http://www.nature.com/nrg/journal/vaop/ncurrent/full/nrg3112.html

  1. Lindblad-Toh, K. et al. A high-resolution map of human evolutionary constraint using 29 mammals. Nature 12 Oct 2011 (doi: 10.1038/nature10530)
  2. Lin, M. F. et al. Locating protein-coding sequences under selection for additional, overlapping functions in 29 mammalian genomes. Genome Res. 12 Oct 2011 (doi: 10.1101/gr.108753.110)