compromise, render

I am prepared to make some concession on minor details, but I cannot compromise on fundamentals. 

在一些细节上我可以作些让步，但在基本原则上我是不会妥协的。

The loss of variation and the cost of domestication in genomes of crop species 

may compromise the level of natural defenses against pathogens 

and render them more susceptible than their wild relatives.