multiple sequence alignment - DIALIGN-TX

Introduction:

DIALIGN-TX is a substantial improvement of DIALIGN-T that combines greedy and progressive alignment strategies in a new algorithm which is now available for download. Further information can be found in:

• Abstract of DIALIGN-TX
• Short outline of the algorithmic improvements
• Benchmark results and construction of IRMBASE 2 and DIRMBASE 1

Further Information and Citation

More detailed descriptions of the methods can be found in:

• Amarendran R. Subramanian, Michael Kaufmann, Burkhard Morgenstern:
  DIALIGN-TX: greedy and progressive approaches for segment-based multiple sequence alignment
  Algorithms for Molecular Biology 2008, 3:6
• Amarendran R. Subramanian, Jan Weyer-Menkhoff, Michael Kaufmann, Burkhard Morgenstern:
  DIALIGN-T: An improved algorithm for segment-based multiple sequence alignment
  BMC Bioinformatics 2005, 6:66.

Research work using DIALIGN-TX/DIALIGN-T should cite the above mentioned publications.

http://dialign-tx.gobics.de/

http://dialign-tx.gobics.de/submission?type=dna