evolving all we are
2012年8月6日星期一
Detect recombination events from population genomic data
1.
Population
Genomics
of
Early
Events
in
the
Ecological
Differentiation
of
Bacteria
2.
Detection
of
recombination
events
in
bacterial
genomes
from
large
population
samples
The
model
above
is
developed
for
the
detection
of
recombinant
material
introduced
into
a
closely
related
set
of
bacteria
over
the
process
of
their
diversification
.
The
design
is
motivated
by
data
sets
of
individual
virulent
or
drug
resistant
lineages
,
and
it
should
be
noted
that
the
above
model
is
likely
to
be
sub-optimal
for
the
analysis
of
data
from
highly
structured
populations
(
as
observed
in
our
simulations
where
both
false
and
true
positive
rates
decreased
when
overall
genetic
diversity
increased
).
We
are
currently
developing
the
proposed
model
and
the
inference
algorithm
to
handle
such
issues
and
generalize
the
method
to
alternative
data
sets
.
3.
Identifying
Currents
in
the
Gene
Pool
for
Bacterial
Populations
Using
an
Integrative
Approach
Additionally
,
we
used
the
BAPS
program
(
Bayesian
Analysis
of
Population
Structure
)
36
to examine clustering of the isolates on the basis of SNP data.
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