2. GenomicTools
2012年7月22日星期日
two NGS tools
1. MolBioLib
MolBioLib is a compact efficient C ++11 programming framework with accompanying set of tools enabling rapid development and deployment of next-generation sequencer data analysis programs . The library includes objects to aid in storage of relational data , traversal of delimited files , and manipulation of sequence files . Methods range from alignment writers to statistical functions and string manipulations . Tools to manipulate TSV files , count aligned hits to features such as genes , coverage , and ChIP-Seq are included .
2. GenomicTools
GenomicTools is a flexible computational platform for the analysis and manipulation of high-throughput sequencing data such as RNA-seq and ChIP-seq . GenomicTools implements a variety of mathematical operations between sets of genomic regions thereby enabling the prototyping of computational pipelines that can address a wide spectrum of tasks from preprocessing and quality control to meta-analyses . More specifically , the user can easily create average read profiles across transcriptional start sites or enhancer sites , quickly prototype customized peak discovery methods for ChIP-seq experiments , perform genome-wide statistical tests such as enrichment analyses , design controls via appropriate randomization schemes , among other applications . In addition to enabling rapid prototyping , the GenomicTools platform is designed to analyze large-datasets in a single-pass fashion in order to minimize memory and intermediate file requirements . Finally , the GenomicTools platform supports the widely used BED format to facilitate visualization as well as integration with existing platforms and pipelines such as Galaxy or BioConductor.
2. GenomicTools
订阅:
博文评论 (Atom)
没有评论:
发表评论